教育经历
- 2013-2014，香港中文大学，生命科学学院，硕士
- 2015-2020，香港中文大学，生命科学学院，博士
工作经历
- 2011-2012，香港中文大学生命科学学院，初级研究助理
- 2020-2021，香港中文大学生命科学学院，副研究员
- 2021-至今，上海交通大学农业与生物学院，长聘教轨副教授
研究内容
- 本课题组主要围绕细胞器与作物性状（包括耐高温胁迫等）调控机制开展研究，以粮食作物水稻、园艺作物番茄和模式植物拟南芥等作为材料，结合细胞生物学(超分辨显微技术，电子显微技术等)、分子生物学、遗传学和生物信息学等多种方法从亚细胞微观角度出发，探索植物细胞器响应逆境的信号通路, 解析细胞器与植物抗逆胁迫的关系，为作物抗逆改良提供重要理论基础，为全球气候变化带来的粮食安全问题提供新的解决方案。目前主要研究内容包括：
- 1. 植物细胞器感知热胁迫信号的通路及其耐热机制；
- 2. 作物抗逆和生长发育的协同调控机制；
- 3. 自噬信号通路调控与自噬体形成的分子机制。
承担项目
- 国家级海外高层次人才（青年）项目、国家重点研发项目、上海市海外高层次人才（青年）项目、浦江人才计划项目和上海交通大学“2030计划”项目等。
论文
- Shuang-Qin Guo, Ya-Xin Chen, Ya-Lin Ju, Chen-Yang Pan, Jun-Xiang Shan, Wang-Wei Ye, Nai-Qian Dong, Yi Kan, Yi-Bing Yang, Huai-Yu Zhao, Hong-Xiao Yu, Zi-Qi Lu, Jie-Jie Lei, Ben Liao, Xiao-Rui Mu, Ying-Jie Cao, Liangxing Guo, Jin Gao, Ji-Fu Zhou, Kai-Yang Yang, Hong-Xuan Lin*, Youshun Lin* (2025). Fine-tuning gibberellin improves rice alkali–thermal tolerance and yield. Nature 639: 162-171. (* co-corresponding author)
- Hai Zhang, Ji-Fu Zhou, Yi Kan, Jun-Xiang Shan, Wang-Wei Ye, Nai-Qian Dong, Tao Guo, You-Huang Xiang, Yi-Bing Yang, Ya-Chao Li, Huai-Yu Zhao, Hong-Xiao Yu, Zi-Qi Lu, Shuang-Qin Guo, Jie-Jie Lei, Ben Liao, Xiao-Rui Mu, Ying-Jie Cao, Jia-Jun Yu, Youshun Lin*, Hong-Xuan Lin* (2022). A genetic module at one locus in rice protects chloroplasts to enhance thermotolerance. Science 376 (6599): 1293-1300. (* co-corresponding author)
- Yi Kan, Xiao-Rui Mu, Jin Gao, Hong-Xuan Lin*, and Youshun Lin* (2023). The molecular basis of heat stress responses in plants. Molecular Plant 16(10): 1612-1634. (* co-corresponding author)
- Youshun Lin*, Yonglun Zeng, Ying Zhu, Jinbo Shen, Hao Ye, Liwen Jiang* (2021). Plant Rho GTPase signaling promotes autophagy. Molecular Plant 14(6): 905-920. (* co-corresponding author)
- Youshun Lin, Rongfang Guo, Changyang Ji*, Jun Zhou*, Liwen Jiang* (2021). New insights into AtNBR1 as a selective autophagy cargo receptor in Arabidopsis. Plant Signaling & Behavior 16(1): 1839226.
- Youshun Lin#, Yu Ding#, Juan Wang, Jinbo Shen, Chun Hong Kung, Xiaohong Zhuang, Yong Cui, Zhao Yin, Yiji Xia, Hongxuan Lin, David G. Robinson, Liwen Jiang* (2015). Exocyst-positive organelles and autophagosomes are distinct organelles in plants. Plant Physiology 169(3): 1917-1932. (# co-first author)
- Chen Chen#, Hao Chen#, Youshun Lin#, Jinbo Shen, Junxiang Shan, Peng Qi, Min Shi, Meizhen Zhu, Xuehui Huang, Qi Feng, Bin Han, Liwen Jiang, Jiping Gao*, Hongxuan Lin* (2014). A two-locus interaction causes interspecific hybrid weakness in rice. Nature Communications 5(1): 3357. (# co-first author)
- Peng Qi#, Youshun Lin#, Xianjun Song#, Jinbo Shen, Wei Huang, Junxiang Shan, Meizhen Zhu, Liwen Jiang, Jiping Gao*, Hongxuan Lin* (2012). The novel quantitative trait locus GL3.1 controls rice grain size and yield by regulating Cyclin-T1;3. Cell Research 22(12): 1666-1680. (# co-first author)
- 其他作者论文
- Yilin He, Jiayang Gao, Luo Mengqian, Caiji Gao, Youshun Lin, Hiu Yan Wong, Yong Cui, Xiaohong Zhuang, Liwen Jiang* (2023). VAMP724 and VAMP726 are involved in autophagosome formation in Arabidopsis thaliana. Autophagy 19(5): 1406-1423.
- Hao Ye, Jiayang Gao, Zizhen Liang, Youshun Lin, Qianyi Yu, Shuxian Huang, Liwen Jiang* (2022). Arabidopsis ORP2A mediates ER-autophagosomal membrane contact sites and regulates PI3P in plant autophagy. Proceedings of the National Academy of Sciences 119(43): e2205314119.
- Yonglun Zeng, Baiying Li, Changyang Ji, Lei Feng, Fangfang Niu, Cesi Deng, Shuai Chen, Youshun Lin, Kenneth C.P. Cheung, Jinbo Shen, Kam Bo Wong, Liwen Jiang* (2021). A unique AtSar1D-AtRabD2a nexus modulates autophagosome biogenesis in Arabidopsis thaliana. Proceedings of the National Academy of Sciences 118(17): e2021293118.
- Liu Hong, Fangfang Niu*, Youshun Lin, Shuang Wang, Liyuan Chen* and Liwen Jiang (2021). MYB106 is a negative regulator and a substrate for CRL3BPM E3 ligase in regulating flowering time in Arabidopsis thaliana. Journal of Integrative Plant Biology 63(6): 1104-1119.
- Liu Hong, Fangfang Niu*, Youshun Lin, Shuang Wang, Liyuan Chen* and Liwen Jiang (2021). MYB117 is a negative regulator of flowering time in Arabidopsis. Plant Signaling & Behavior 16(5): 1901448.
- Yonglun Zeng, Changyang Ji, Youshun Lin, Liwen Jiang (2021). Transient Expression of Fluorescent Fusion Proteins in Arabidopsis Protoplasts. Methods in Molecular Biology - Arabidopsis Protocols 2200: 157-165.
- Changyang Ji, Jun Zhou, Rongfang Guo, Youshun Lin, Chun Hong Kung, Shuai Hu, Wing Yin Ng, Xiaohong Zhuang, Liwen Jiang* (2020). AtNBR1 Is a Selective Autophagic Receptor for AtExo70E2 in Arabidopsis. Plant Physiology 184(2): 777-791.
- Yonglun Zeng*, Baiying Li*, Youshun Lin, Liwen Jiang* (2019). The interplay between endomembranes and autophagy in plants. Current Opinion in Plant Biology 52: 14-22.
- Jinbo Shen, Caiji Gao, Qiong Zhao, Youshun Lin, Xiangfeng Wang, Xiaohong Zhuang, Liwen Jiang* (2016). AtBRO1 functions in ESCRT-I complex to regulate multivesicular body protein sorting. Molecular Plant 9(5): 760-763.
- Jinbo Shen, Pui Kit Suen, Xiangfeng Wang, Youshun Lin, Sze Wan Lo, Enrique Rojo, Liwen Jiang* (2013). An in vivo expression system for the identification of cargo proteins of vacuolar sorting receptors in Arabidopsis culture cells. Plant Journal 75(6): 1003-1017.
专利著作
- Hai Zhang, Ji-Fu Zhou, Yi Kan, Jun-Xiang Shan, Wang-Wei Ye, Nai-Qian Dong, Tao Guo, You-Huang Xiang, Yi-Bing Yang, Ya-Chao Li, Huai-Yu Zhao, Hong-Xiao Yu, Zi-Qi Lu, Shuang-Qin Guo, Jie-Jie Lei, Ben Liao, Xiao-Rui Mu, Ying-Jie Cao, Jia-Jun Yu, Youshun Lin*, Hong-Xuan Lin*. A genetic module at one locus in rice protects chloroplasts to enhance thermotolerance; Science. 376(6599) (2022): 1293-1300. (* co-corresponding author)
- Yi Kan, Xiao-Rui Mu, Jin Gao, Hong-Xuan Lin*, and Youshun Lin*. The molecular basis of heat stress responses in plants; Molecular Plant. 16(10) (2023): 1612-1634. (* co-corresponding author)
- Youshun Lin*, Yonglun Zeng, Ying Zhu, Jinbo Shen, Hao Ye, Liwen Jiang*. Plant Rho GTPase signaling promotes autophagy; Molecular Plant. 14(6) (2021), 905-920. (* co-corresponding author)
- Youshun Lin, Rongfang Guo, Changyang Ji*, Jun Zhou*, Liwen Jiang*. New insights into AtNBR1 as a selective autophagy cargo receptor in Arabidopsis; Plant Signaling & Behavior; 16(1) (2021), p.1839226.
- Youshun Lin#, Yu Ding#, Juan Wang, Jinbo Shen, Chun Hong Kung, Xiaohong Zhuang, Yong Cui, Zhao Yin, Yiji Xia, Hongxuan Lin, David G. Robinson, Liwen Jiang*. Exocyst-positive organelles and autophagosomes are distinct organelles in plants; Plant Physiology; 169(3) (2015), 1917-1932.
- Chen Chen#, Hao Chen#, Youshun Lin#, Jinbo Shen, Junxiang Shan, Peng Qi, Min Shi, Meizhen Zhu, Xuehui Huang, Qi Feng, Bin Han, Liwen Jiang, Jiping Gao*, Hongxuan Lin*. A two-locus interaction causes interspecific hybrid weakness in rice; Nature Communications, 5(1) (2014), 1-11.
- Peng Qi#, Youshun Lin#, Xianjun Song#, Jinbo Shen, Wei Huang, Junxiang Shan, Meizhen Zhu, Liwen Jiang, Jiping Gao*, Hongxuan Lin*. The novel quantitative trait locus GL3.1 controls rice grain size and yield by regulating Cyclin-T1;3; Cell Research, 22(12) (2012), 1666-1680.
- Yilin He, Jiayang Gao, Luo Mengqian, Caiji Gao, Youshun Lin, Hiu Yan Wong, Yong Cui, Xiaohong Zhuang, Liwen Jiang*. VAMP724 and VAMP726 are involved in autophagosome formation in Arabidopsis thaliana; Autophagy, 19(5) (2023), 1406-1423.
- Hao Ye, Jiayang Gao, Zizhen Liang, Youshun Lin, Qianyi Yu, Shuxian Huang, Liwen Jiang*. Arabidopsis ORP2A mediates ER-autophagosomal membrane contact sites and regulates PI3P in plant autophagy; Proceedings of the National Academy of Sciences, 119(43) (2022), e2205314119.
- Yonglun Zeng, Baiying Li, Changyang Ji, Lei Feng, Fangfang Niu, Cesi Deng, Shuai Chen, Youshun Lin, Kenneth C.P. Cheung, Jinbo Shen, Kam Bo Wong, Liwen Jiang*. A unique AtSar1D-AtRabD2a nexus modulates autophagosome biogenesis in Arabidopsis thaliana; Proceedings of the National Academy of Sciences, 118(17) (2021), e2021293118.
- Liu Hong, Fangfang Niu*, Youshun Lin, Shuang Wang, Liyuan Chen* and Liwen Jiang. MYB106 is a negative regulator and a substrate for CRL3BPM E3 ligase in regulating flowering time in Arabidopsis thaliana; Journal of Integrative Plant Biology, (2021), 1104-1119.
- Liu Hong, Fangfang Niu*, Youshun Lin, Shuang Wang, Liyuan Chen* and Liwen Jiang. MYB117 is a negative regulator of flowering time in Arabidopsis. Plant Signaling & Behavior, (2021), 1901448.
- Changyang Ji, Jun Zhou, Rongfang Guo, Youshun Lin, Chun Hong Kung, Shuai Hu, Wing Yin Ng, Xiaohong Zhuang, Liwen Jiang*. AtNBR1 Is a Selective Autophagic Receptor for AtExo70E2 in Arabidopsis; Plant Physiology, 184(2) (2020), 777-791.
- Yonglun Zeng*, Baiying Li*, Youshun Lin, Liwen Jiang*. The interplay between endomembranes and autophagy in plants; Current Opinion in Plant Biology, 52 (2019), 14-22.
- Jinbo Shen, Caiji Gao, Qiong Zhao, Youshun Lin, Xiangfeng Wang, Xiaohong Zhuang, Liwen Jiang*. AtBRO1 functions in ESCRT-I complex to regulate multivesicular body protein sorting; Molecular Plant, 9(5) (2016), 760-763.
- Jinbo Shen, Pui Kit Suen, Xiangfeng Wang, Youshun Lin, Sze Wan Lo, Enrique Rojo, Liwen Jiang*. An in vivo expression system for the identification of cargo proteins of vacuolar sorting receptors in Arabidopsis culture cells; Plant Journal, 75(6) (2013), 1003-1017.
荣誉
- 在水稻高温感知和耐高温新基因及其上下游的分子调控网络研究方面取得重要进展，水稻耐高温机制的合作研究成果入选2022年度“中国生命科学十大进展”。