Department of Animal Science

Address: Room 0-406, School of Agriculture and Biology.

Phone: +86 15921185068






Since 2020 Prof., Shanghai Jiaotong University, China

2015-2020 Associate Prof., Shanghai Jiaotong University, China

2012-2013 Visiting Prof, University of California, San Francisco, USA

2009-2014 Assistant Prof., Shanghai Jiaotong University, China



Selected Award & Honors

Tang lixin outstanding Faculty Award, Shanghai Jiaotong University, 2017.

LI-lanxin outstanding Youth Faculty Award, Shanghai Jiaotong University, 2016.

SMC-Excellent Youth Faculty Award, Shanghai Jiaotong University, 2012.



Selected Memberships:

Since 2018 Editor-in-Chief of Comparative Immunology, Microbiology and Infectious Diseases

Since 2016 Editorial board of American Journal of Infectious Diseases



Research Funding

1. Mechanism of pro-apoptotic effect of Bartonella bepC through interacting with p53 protein. NSFC/31400124

Role: Principal Investigator

2. Promote host cell migration by Bartonella T4SS effector BepE through activation of GTPases. NSFC/31972653

Role: Principal Investigator

3. Vertical evolutionary patterns and mechanisms of host adaption of rodent-associated Bartonella. STCSM/18490712700.

Role: Principal Investigator



Research overview:

Infectious diseases by pathogen from companion animal with zoonotic significance are a growing problem in today's society, e.g. Rabies, Toxoplasmosis, Ehrlichiosis, Bartonellosis, Bordetellosis. Research in my laboratory is focused on the pathogensis of Bartonella infection (causing cat scratch disease) with particularly interests in understanding the function of bacterial effector proteins injected into host cell by type IV secretion system.



Featured Publications:

  1. Wang C, Haoran Zhang, Jiaqi Fu, Meng Wang, Yuhao Cai, Tianyun Ding, Jiezhang Jiang, Xiaoyun Liu, Jane E Koehler, Congli Yuan*. Bartonella type IV secretion effector BepC induces stress fiber formation through activation of GEF-H1, PLoS Pathogens. 2020. Ahead of publication
  2. Wang C, Fu J, Wang M, Cai Y, Hua X, Du Y, Yang Z, Li Y, Wang Z, Sheng H, Yin N, Liu X, Koehler JE, Congli Yuan*. Bartonella quintana type IV secretion effector BepE-induced selective autophagy by conjugation with K63 polyubiquitin chain. Cell Microbiol. 2019 Apr;21(4):e12984.
  3. Jiehua Hong,Yan Li ,Xiuguo Hua,Yajie Bai,Chunyan Wang,Zhibiao Yang,Yuming Du,Congli Yuan*. Lymphatic Circulation Disseminates Bartonella Infection Into Bloodstream,Journal of Infectious Diseases,2017.01.03,215:303~311
  4.  Caixia Zhu,Yajie Bai,Qiyong Liu,Dongmei Li,Jiehua Hong,Zhibiao Yang,Li Cui,Xiuguo Hua,Congli Yuan*. Depolymerization of cytokeratin intermediate filaments facilitates intracellular infection of HeLa cells by Bartonella henselae. Journal Infectious Diseases,2013.5.1,207(9)
  5. Congli Yuan, Caixia Zhu, Yanbing Wu, Xueying Pan, Xiuguo Hua. Bacteriological and Molecular Identification of Bartonella Species in Cats from Different Regions of China,PLoS Neglected Tropical Diseases,2011.9.01
  6. Congli Yuan,Patrick J Keeling,Peter J Krause,Ales Horak,Stephen Bent,Lindsay Rollend,Xiuguo Hua. Colpodella spp.-like parasite infection in woman, China.,Emerging Infectious Diseases,2012.1.01,18(1):125~127



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