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杨仲南

职称：特聘教授
所属学科：植物科学系
研究方向：
  1. 植物花药与花粉发育
  2. 光温敏不育机制与作物两系杂交制种
  3. 细胞质不育与核质互作调控育性机制
电子信箱：znyang@sjtu.edu.cn
联系地址：上海交通大学农业与生物学院

 

个人简历

杨仲南，博士，教授，博士生导师。1987年南京大学本科毕业后到中科院上海植物生理所硕博连读，1993年博士毕业后留所工作。1995-2001年美国Texas A&M大学博士后。2002-2024上海师范大学，教授。2025年调到上海交通大学农业与生物学院工作。目前主要学术兼职有中国细胞生物学会 发育生物学分会副会长(2023-2026)，中国遗传学会 细胞遗传学分会副主任委员(2023-2028)。

 

主要研究内容（聚焦植物花粉/小孢子）

  1. 植物花药发育与花粉形成机制：通过雄性不育突变体克隆花药发育关键基因；从细胞、遗传、生化及分子水平解析花药各层细胞(小孢子母细胞、绒毡层、中层及药室内壁细胞)的发育，以及与花粉形成的关系。代表性的工作是解析了绒毡层细胞的遗传通路及对花粉形成的级联调控机制，具体见综述(Yao et al., Seed Biology 1:5,2022)。

  1. 光温敏不育机制与作物两系杂交制种：两系杂交水稻依赖光温敏不育系，育性稳定的光温敏不育系缺乏是当前水稻杂交制种的瓶颈。课题组解析了光温敏的机制：低温或短光照条件下的缓慢发育和活性氧(ROS)有效清除是育性恢复的共性机制，不同基因突变导致的光温敏不育系还有各自育性恢复机制。具体见综述(Wang et al., Molecular Plant  18:26-41，2025)。在此基础上创制了水稻、玉米光温敏不育系，其中ostms15、ostms16、ostms18和ostms19已发表。ostms15已在国内约三十家育种单位应用。

  1. 细胞质不育与核质互作调控育性机制：细胞质雄性不育在作物三系杂交制种和园艺植物制种中起关键的作用。近几年课题组已从分子和细胞水平研究细胞质不育及核质互作机制，创制了一批相关的遗传材料（至今尚未发表论文）。相关的研究将深入解析作物和园艺植物细胞质雄性不育系核质互作的机制，也将破解蔬菜等园艺植物和作物不育系育性恢复的难题。

 

 

主持的主要科研项目

  1. 国家重点研发计划课题：主要农作物光温湿等条件不育调控基因及分子机理. 2022.12-2027.11
  2. 国家自然科学基金面上项目：花粉外被与柱头互作启动花粉水合机制，2025-2028.
  3. 国家自然科学基金重点项目：温度调控花粉壁发育的机理，2020-2024。
  4. 国家自然科学基金面上项目：花粉表面蛋白在花粉发育、花粉与柱头识别中的作用，2019-2022。
  5. 国家自然科学基金面上项目：花药中层细胞发育及调控。2017-2020。
  6. 国家自然科学基金面上项目：拟南芥PPR基因AtECB2调控叶绿体转录本编辑及叶绿体发育的分子机理，2014-2017.
  7. 国家杰出青年科学基金：模式植物拟南芥花粉壁形成的分子机理，2010-2013。
  8. 国家自然科学基金面上项目：转录因子TDF1结合位点分析及直接调控下游基因的鉴定。2008-2010。
  9. 国家自然科学基金重点项目：转录因子MYB103调控花粉发育的分子机理。2006-2009。
  10. 国家自然科学基金面上项目：拟南芥花粉发育必需基因的克隆及功能分析。2005-2007。
  11. 科技部重大科学研究计划课题：花粉表面识别物质的鉴定，2007-2011。
  12. 上海市优秀学科带头人：CDKG1调控花药发育的分子机理， 2011.6-2013.5
  13. 上海市教委科研创新重点项目：植物光温敏育性调控机理。2019-2023。

 

获奖情况：

  1. 2017年上海市自然科学三等奖《植物雄性不育及花粉发育》. 证书号：20172017-3-R01。
  2. 2019年上海市自然科学三等奖《植物质体基因表达调控》. 证书号：20192043-3-R01.
  3. 爱思唯尔2020,2023年度中国高被引作者(生物学领域).
  4. “新型水稻光温敏不育系的创制”研究成果获选“2024中国农业农村重大新技术新产品新装备”。

 

代表性授权专利：

  1. 杨仲南,朱骏,张森,周文涛,周鹊. 创制光温敏不育系的方法及其在植物育种中的应用. 申请号：PCT/CN2015/096027. 专利号：特许第6524252号。
  2. Zhongnan Yang, Jun Zhu, Yueling Li, Yanfei Zhang. Rice thermo-sensitive male sterile gene mutant tms18 and uses thereof. Patent No: US 11,761,017 B Sep 19, 2023 (关于水稻光温敏不育系tms18美国授权专利)

 

主要论文及著作：

自2002年建立实验室以来，以最后通讯作者在Nature Plants (2), Nature Communications (2), Plant Cell (1), Molecular Plant (7), Cell Research(1)，Plant Biotechnology Journal (3), Plant Physiology (12), Plant Journal (11)等国际本学科主流期刊发表系列论文. (“必看论文”指希望来本实验室学习的同学必须反复学习的论文)

  1. Wang N, Li X, Zhu J, Yang ZN*. 2025. Molecular and Cellular Mechanisms of Photoperiod and Thermo-sensitive Genic Male Sterility in Plants. Molecular Plant 18(1):26-41. （必看论文）
  2. Yao XZ, Hu Wen, and Yang ZN*, 2022. The contributions of sporophytic tapetum to pollen formation. Seed Biology 1:5. （必看论文）
  3. Ma C, Wang SH, Yang YM, Fu J, Guo MD, Chen X, Mao YC, Huang XH, Zhu J*, Yang ZN*. 2025. ATP-Citrate Lyase ACLB-1 is critical for sporopollenin synthesis and energy supply for microspore development. Plant Physiology. 197(2)
  4. Zhou L, Mao YC, Yang YM, Wang JJ, Zhong X, Han Y, Zhang YF, Shi QS, Huang XH, Blake C. Meyers, Zhu J*, Yang ZN*. 2024. Temperature and light reverse the fertility of rice P/TGMS line ostms19 via ROS homeostasis. Plant Biotechnology Journal. 22: 2020-2032. (报导Ostms19光温敏不育系及光温敏不育共性机制)
  5. Chen X†, Huang DD†, Xue JS†, Bu JH, Zhang MQ, Wang N, Huang JR, Chen WS* and Yang ZN*. 2024. Polymeric phenylpropanoid derivatives crosslinked by hydroxyl fatty acids form the core structure of rape sporopollenin. Nature Plants 10: 1790-1800 (孢粉素结构解析)
  6. Zhang C, Xiong AT, Ren MY, Zhao YY, Huang MJ, Huang LC, Zhang Z, Wang Y, Zheng QQ, Fan J, Guan JJ and Yang ZN*. 2024. An epigenetically mediated double negative cascade from EFD to HB21 regulates anther development. Nature Communications 14, 7796. (表观遗传对花药发育的全局调控)
  7. Zhang Z, Guo YY, Wang YC, Zhou L, Fan J, Mao YC, Yang YM, Zhang YF, Huang XH, Zhu J, Zhang C*, Yang ZN*. 2024. A point mutation in a meiotic crossover formation gene HEI10/TFS2 leads to thermosensitive genic female sterility in rice. Plant Journal 118: 506-518. (报导水稻雌性光温敏不育系tfs2)
  8. Xue JS, Feng YF, Zhang MQ, Xu QL, Xu YM, Shi JQ, Liu LF, Wu XF, Wang S, and Yang ZN*. 2024. The regulatory mechanism of rapid lignification for timely anther dehiscence. JIPB 66(8):1788-1800. (花药快速木质化调控花粉释放的机制)
  9. Han Y, Jiang SZ, Zhong X, Chen X, Ma CK, Yang YM, Mao YC, Zhou SD, Zhou L, Zhang YF, Huang XH, Zhang H, Li LG, Zhu J*, Yang ZN*. 2023. Low temperature compensates the defective tapetum initiation to restore the fertility of a novel TGMS line ostms15. Plant Biotechnology Journal 21:1659-1670 (报导Ostms15光温敏不育系)
  10. Xue JS, Qiu S, Jia XL, Shen SY, Shen CW, Wang S, Xu P, Tong Q, Lou YX, Yang NY, Cao JG, Hu JF, Shen H, Zhu RL, Murray JD, Chen WS*, Yang ZN*. 2023. Stepwise changes in flavonoids in spores/pollen contributed to terrestrial adaptation of plants. Plant Physiology 193(1):627-642
  11. Zhang YF†, Li YL†, Zhong X, Wang JJ, Zhou L, Han Y, Li DD, Wang N, Huang XH, Zhu J*, Yang ZN*. 2022. Mutation of the GMC oxidoreductase leads to thermo-sensitive genic male sterility in rice and Arabidopsis. Plant Biotechnology Journal 20:2023-2035. (报导Ostms18光温敏不育系)
  12. Zhang C†, Ren MY†, Han WJ†, Zhang YF, Huang MJ, Wang Y, Zhang Z, Wu SY, Huang J, Yang ZN*. 2022. Slow development allows redundant genes to restore the fertility of rpg1, a TGMS line in Arabidopsis. Plant Journal 109: 1375-1385
  13. Shi QS†, Lou Y†, Shen SY, Wang KQ, Wang SH, Zhou L, Wang JJ, Liu XL, Xiong SX, Han Y, Zhou HS, Huang XH, Wang S, Zhu J*, Yang ZN*. 2021. A cellular mechanism underlying the restoration of thermo/photoperiod-sensitive genic male sterility. Molecular Plant 14:2104-2114.
  14. Zhang C†, Xu T†, Ren MY†, Zhu J, Shi QS, Zhang YF, Qi YW, Huang MJ, Song L, Xu P*, Yang ZN*. 2020. Slow development restores the fertility of photoperiod-sensitive male sterile plant lines. Plant Physiology 184(2): 923-932
  15. Lu JY†, Xiong SX†, Yin WZ†, Teng XD, Lou Y, Zhu J, Zhang C, Gu JN, Wilson ZA*, Yang ZN*. 2020. MS1, a direct target of MS188, regulates the expression of key sporophytic pollen coat protein genes in Arabidopsis thaliana. Journal Experimental Botany 71(16): 4877-4889. 
  16. Xue JS†, Zhang BC†, Zhan HD†, Lv YL, Jia XL, Wang TH, Yang NY, Lou YX, Zhang ZB, Hu WJ, Gui JS, Cao JG, Xu P, Zhou YH, Hu JF, Li LG*, Yang ZN*. 2020. Phenylpropanoid derivatives are essential components of sporopollenin in vascular plants. Molecular Plant 13: 1644-1653
  17. Zhu J†, Lou Y†, Shi QS†, Zhang S†, Zhou WT, Yang J, Zhang C, Yao XZ, Xu T, Liu JL, Wang S, Huang XH, Yang ZN*. 2020. Slowing development restores the fertility of thermo-sensitive male-sterile plant lines. Nature Plants 6: 360-367
  18. Xiong HB, Huang C, Wang J, Rochaix JD, Lin FM, Zhang JX, Ye LS, Shi XH, Yu QB*, and Yang ZN*. 2020. mTERF8, a Member of the Mitochondrial Transcription Termination Factor Family, is Involved in the Transcription Termination of Chloroplast Gene psbJ. Plant Physiology. 182: 408-423.
  19. Xu XF†, Wang B†, Feng YF†, Xue JS, Qian XX, Liu SQ, Zhou J, Yu YH, Yang NY, Xu P, Yang ZN*. 2019. AUXIN RESPONSE FACTOR17 directly regulates MYB108 for anther dehiscence. Plant Physiology 181: 645-655.
  20. Zhang C†, Teng XD†, Zhao YY, Lu JY, Wang YC, Guo HW*, Yang ZN*. 2018. Ethylene signaling control is critical for female gametophyte and embryo development. Plant Journal 96(1): 176-187.
  21. Wang K, Guo ZL, Zhang C,Zhang ZY, Lou Y, Xiong SX, Yao XZ, Fan JJ, Zhu J* and Yang ZN*. 2018. The MYB transcription factor MS188 directly regulates the expressions of sporopollenin synthesis genes for pollen wall formation. Plant Physiology 178: 283-294.
  22. Yao XZ, Tian L, Yang J, Zhao YN, Zhu YX, Dai XH, Zhao YD* & Yang ZN*. 2018. Auxin production in diploid microsporocytes is necessary and sufficient for early stages of pollen development. PLoS Genetics 14 (5): e1007397.
  23. Zhan HD, Xiong HB, Wang S and Yang ZN*. 2018. Anther endothecium provides pollen coat very-long-chain fatty acids (VLCFAs) for pollen hydration in Arabidopsis. Molecular Plant 11(8):1101-1104
  24. Lou Y, Zhou HS, Han Y, Zeng QY, Zhu J*, and Yang ZN*. 2018. Positive regulation of AMS by TDF1 and the formation of a TDF1–AMS complex are required for anther development in Arabidopsis thaliana. New Phytologist 217: 378-391
  25. Huang C†, Yu QB†, Li ZR, Ye LS, Xu L*, and Yang ZN*. 2017. Porphobilinogen deaminase HEMC interacts with the PPR-protein AtECB2 for chloroplast RNA editing. Plant Journal 92(4): 546-556
  26. Yang ZN. 2016. Regulation of sporopollenin synthesis for pollen wall formation in plant. SCIENCE CHINA-LIFE SCIENCES 59(12): 1335-1337.
  27. Xu T†, Zhang C†, Zhou Q and Yang ZN*. 2016. Pollen wall pattern in Arabidopsis. Science Bulletin 61(11): 832-837. (2013CB945100)
  28. Xu XF, Lou Y, Wang B, Lu JY, Li DD, Li LG, Zhu J*, Yang ZN*. 2015. The Magnesium Transporter 5 Plays an Important Role in Mg Transportation from Tapetum to Microspores in Arabidopsis. Plant Journal 84(5):925-936
  29. Cai CF†, Zhu J†, Lou Y, Guo ZL, Xiong SX, Wang K and Yang ZN*. 2015. Thefunctionalanalysisof OsTDF1revealsaconservedgeneticpathwayfor tapetal development between rice and Arabidopsis. Science Bulletin 60(12): 1073-1082
  30. Jia QS, Zhu J, Xu XF, Lou Y, Zhang ZL, Zhang ZP and Yang ZN*. 2015. Arabidopsis AT-hook protein TEK positively regulates the expression of arabinogalactan proteins (AGPs) for nexine formation. Molecular Plant 8:251-260.
  31. Gu JN†, Zhu J†, Yu Y, Teng XT, Lou Y, Xu XF, Liu JL, Yang ZN*. 2014. DYT1 Directly Regulates the Expression of TDF1 for Tapetum Development and Pollen Wall Formation in Arabidopsis. Plant Journal 80: 1005-1013.
  32. Lou Y†, Xu XF†, Zhu J†, Gu JN, Blackmore S, Yang ZN*. 2014. The Tapetal AHL family protein TEK determines nexine formation in the pollen wall. Nature Communications 5:3855
  33. Yu QB, Kong MM, Zhu J, Jia QS, Jiang Y, Mi HL, Chong K, Yang ZN*. 2014. AtECB1/MRL7, a Thioredoxin-like Fold Protein with Disulfide Reductase Activity, Regulates Chloroplast Gene Expression and Chloroplast Biogenesis in Arabidopsis thaliana. Molecular Plant 7(1):206-217
  34. Yang J, Tian L, Huang XY, Sun MX, Zhu J, Guan YF, and Yang ZN*. 2013. Auxin Response Factor17 is essential for auxin signaling in primexine formation and pollen development. Plant Physiology 162:720-731.
  35. Huang XY, Niu J, Sun MX, Zhu J, Gao JF, Yang J, Zhou Q, and Yang ZN*.2013. CDKG1 is Associated with Splicesome to Regulate CalS5 Splicing and Pollen Wall Formation in Arabidopsis thaliana. Plant Cell 25(2) :637-648
  36. Zhang C, Song Y, Cheng ZH, Wang YX, Zhu J, Ma H, Xu L*, Yang ZN*. 2012. The Arabidopsis thaliana DSB FORMATION (AtDFO) Gene is Required for Meiotic Double Strand Break Formation. Plant Journal. 72(2):271-281
  37. Li XC†, Zhu J†, Yang J, Zhang GR, Xing WF, Zhang S, Yang ZN*. 2012. Glycerol-3-phosphate acyltransferase 6 (GPAT6) is important for tapetum development in Arabidopsis and plays multiple roles in plant fertility. Molecular Plant.5(1): 131-142
  38. Chang HS†, Zhang C†, Chang YH, Zhu J, Xu XF, Shi ZH, Zhang XL, Xu L, Huang H, Zhang S*, and Yang ZN*，2012. NO PRIMEXINE AND PLASMA MEMBRANE UNDULATION (NPU), Is Essential for Primexine Deposition and Plasma Membrane Undulation during Microsporogenesis in Arabidopsis thaliana. Plant Physiology 158(1): 264–272.
  39. Gao ZP, Yu QB, Zhao TT, Ma Q, Chen GX*, and Yang ZN*. 2011. A functional component of transcriptionally active chromosome complex, Arabidopsis pTAC14, interacts with pTAC12 and regulates the plastid gene expression. Plant Physiology 157(4): 1733-1745
  40. Cui YL, Jia QS, Yin QQ, Lin GN, Kong MM, Yang ZN*. 2011. The GDC1 Gene Encodes a Novel Ankyrin Domain Containing Protein That is Essential for Grana Formation in Arabidopsis thaliana. Plant Physiology 155(1):130-141.
  41. Zhu J, Lou Y, Xu XF, and Yang ZN*. 2011. A Genetic Pathway for Tapetum Development and Function in Arabidopsis. Journal of Integrative Plant Biology. 53(11): 892-900.
  42. Yu QB†, Jiang Y†, Chong K*, and Yang ZN*. 2009. AtECB2, a Pentatricopeptide Repeat Protein, is Involved in Chloroplast Transcript accD RNA Editing and Essential for Early Chloroplast Biogenesis in Arabidopsis thaliana. Plant Journal. 59(6):1011-1023.
  43. Jiang H†, Wang FF†, Wu YT†, Zhou X, Huang XY, Zhu J, Gao JF, Dong RB，Cao KM*, Yang ZN*.2009. MULTIPOLAR SPINDLE 1 (MPS1), a novel coiled-coil protein of Arabidopsis thaliana, is required for meiotic spindle organization. Plant Journal. 59(6):1001-1010.
  44. Zhu J†, Chen H†, Li H, Gao JF, Jiang H, Wang C, Guan YF, and Yang ZN*. 2008. Defective of Tapetum Development and Function1 (TDF1) Is Essential for Anther Development and Tapetum Function for Microspore Maturation in Arabidopsis. Plant Journal 55(2): 266-277
  45. Guan YF, Huang XY, Zhu J, Gao JF, Zhang HX and Yang ZN*. 2008. RUPTURED POLLEN GRAIN 1 (RPG1), a Member of MtN3/Saliva Gene Family, is Crucial for Exine Pattern Formation and Cell Integrity of Microspores in Arabidopsis thaliana. Plant Physiology 147(2): 852-862
  46. Yu QB†, Li G†, Wang G†, Sun JC†, Wang PC, Wang C, Mi HL, Ma WM, Cui J, Cui YL,Chong K, Li YX, Li YH, Zhao ZM, Shi TL*, and Yang ZN*. 2008. Construction of a Chloroplast Protein Interaction Network and Functional Mining of Photosynthetic Proteins in Arabidopsis thaliana. Cell Research. 18(10):1007-1019.
  47. Zhang ZB†, Zhu J†, Gao JF†, Wang C, Li H, Zhang HQ, Zhang S, Wang DM, Wang QX, Huang H, Xia HJ, Yang ZN*. 2007. Transcription Factor AtMYB103 is Required for Anther Development by Regulating Microspore Release from Tetrads and Exine Formation in Arabidopsis. Plant Journal 52(3): 528-538。
  48. Shen YJ†, Jiang H†, Jin JP†, Zhang ZB, Xi B, Wang G, Wang C, Qian L, Li X, Yu QB, Liu HJ, Chen DH, Gao JH, Huang H, Shi TL* & ZN Yang*. 2004. Development of genome-wide DNA polymorphism database for map-based cloning of rice genes. Plant Physiology 135：1198-1205

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