PI 组长：

涂晓雨  

Lab Members：

2021级本科生，马晴川，在读

2022级硕士生，李亿宁，在读

2022级博士生，李杨美汇，在读

2023级硕士生，李铭璇，在读

2023级硕转博，杨乐意，在读

2023级博士生，李传顺，在读

2023级博士后，张优，在站

2024级博士生，龙正标，在读

2025级博士后，林堪德，在站

研究方向：

1. C4光合基因的动态调控网络与细胞分工；
2. 光合基因跨物种调控的适应性进化；
3. 作物高光效合成的调控策略工程设计及应用。

近期成果（†, co-first; *, corresponding; in bold, Tu lab members）：

论文：

1. Zhao, C., Yang, J., Ni, A., Chen, H., Su, H., Cheng, Y., Li, X., Zhong, L., Fang, D., Sun, H., Yi, J., Wang, Y., Wang, Y., Ming-ju A.L., Ni, X., Chen, L., Li, H., Yu, G., Wang, Y., Chen, R., Yu, H., Shao, W., Sun, H., Bai, Y., Li, C., Dong, Y., Zou, C., Tu, X., Ma, S., Guo, X., Zhang, G., Wang, P., Liu, H., Wei, T., Gu, Y., Zhu, X., Xu, X.; Comparative spatiotemporal single cell transcriptomes reveal rewiring of pre-existing regulations during emergence of Kranz anatomy in C₄ grasses; bioRxiv
2. Zhu, Y., Ngan, H., Zhu, T., Nan, L., Li, W., Xiao, Y., Zhuo, L., Chen, D., Tu, X., Gao, K., Yan, J., Zhong, S., Yang, N.; Pan-cistrome analysis of the leaf accessible chromatin regions of 214 maize inbred lines; bioRxiv
3. Yan, H., Mendieta, J.P., Zhang, X., Liang, Y., Luo, Z., Marand, A.P., Wang Y., Tu, X., Zhong, S., Wessler, S.R., Schmitz, R.J.^*; Evolution of plant cell-type-specific cis-regulatory elements; bioRxiv
4. Mendieta, J.P., Tu, X., Jiang, D., Yan, H., Zhang, X., Marand, A.P., Zhong, S., Schmitz, R.J.^*; Investigating the cis-regulatory basis of C₃ and C₄ photosynthesis in grasses at single-cell resolution; PNAS, 2024, 121(40):e2402781121
5. Tu, X., Ren, S.^†, Shen, W.^†, Li, J.^†, Li, Y., Li, C., Li, Y., Zong, Z., Xie, W., Grierson, D., Fei, Z., Giovannoni, J., Li, P.^*, Zhong, S.^*; Limited conservation in cross-species comparison of GLK transcription factor binding suggested wide-spread cistrome divergence; Nature Communications, 2022, 13:7632 (Nature Communications featured article：http://www/nature.com/subjects/plant-genetics/ncomms)
6. Zhang, Y., Ma, M.^†, Liu, M.^†, Sun, A.^†, Zheng, X., Liu, K., Yin, C., Li, C., Jiang, C.^*, Tu, X.^* (co-corresponding), Fang, Y.^*; Histone H2A monoubiquitination marks are targeted to specific sites by cohesin subunits in Arabidopsis; Nature Communications, 2023, 14:1209 (Nature Communications featured article：http://www/nature.com/subjects/plant-evolution/ncomms)
7. Tu, X., Marand, A.P.^†, Schmitz, R.J.^*, Zhong, S.^*; A combinatorial indexing strategy for low-cost epigenomic profiling of plant single cells; Plant Communications, 2022, 3:100308
8. Dai, X., Tu, X.^† (co-first), Du, B., Dong, P., Sun, S., Wang, X., Sun, J., Gang, L., Lu, T.^*, Zhong, S.^*, Li, P.^*; Chromatin and regulatory differentiation between bundle sheath and mesophyll cells in maize; Plant Journal, 2022, 109(3):675-692
9. Sun, A., Yin, C., Ma, M., Zhou, Y., Zheng, X., Tu, X., Fang, Y.; Feedback regulation of auxin signaling through the transcription of H2A.Z and deposition of H2A.Z to SMALL AUXIN UP RNAs in Arabidopsis; New Phytologist, 2022, 236(5):1721-1733
10. Wang, X., Wang, X.^†*, Sun, S., Tu, X., Lin, K., Qin, L., Wang, X., Li, G.^*, Zhong, S.^*, Li, P.^*; Characterization of regulatory modules controlling leaf angle in maize; Plant Physiology, 2022, 190(1):500-515

专利：

1. 涂晓雨，李杨美汇，张优，李传顺，龙正标：一种基于染色质预富集的高效植物ChIPmentation方法，申请号：2025100973451