学术沙龙第二十一期:无冰晶损伤的生物组织等容冷冻技术

Published:2021-06-22  Views:3385

报 告 人:吕陈昂   食品科学与工程系 助理研究员

   间:2021年6月30日 (星期三) 12:40-14:00

   点:农生学院创新楼(B楼)104会议室

主办单位:农生学院学科与科技办、农生学院青年教师联谊会

 

 

报告题目:无冰晶损伤的生物组织等容冷冻技术

报告摘要:

等容冷冻技术(Isochoric Freezing)利用等容环境下冰晶生长受到抑制的原理,在没有添加抗凝剂的情况下可实现使保存的生物组织温度处于零下而无冰晶损伤。等容冷冻罐中的水在不同温度范围展现出不同的相变特性:-5 ℃~ 0 ℃,表现为较稳定的超冷水状态;-22 ℃~ -5 ℃,表现为高压的(最高压力210 MPa)水-冰平衡状态;液氮速冷条件下则展示出玻璃态的特性。利用上述特性,等容冷冻技术在生鲜食品的零下保鲜,冷冻食品的杀菌灭毒,和组织器官保存等领域展现了较好的前景。本报告将概述性地介绍等容冷冻技术在上述领域的典型研究,如对常规冷冻下品质下降严重的食品(浆果、鱼肉等)的零下保鲜;对大肠杆菌、单核细胞增生李斯特菌、沙门氏菌,蜡样芽孢杆菌及其芽孢的灭活;以及在器官芯片低温运输,器官保存方面的研究。

报告人简介:

报告人2013年获浙江大学生物系统工程学士学位,2018年获浙江大学生物系统工程博士学位,2016-2017年在美国加州大学伯克利分校进行联合培养博士研究生,2018-2020年在美国加州大学伯克利分校进行博士后研究,2020年9月入职农生学院。

【PI学科组研究方向】:

报告人所在的王大鹏研究员课题组主要开展食源性病毒污染与控制方面的研究。主要研究方向如下:

(1)食源性病毒与传播载体的互作机制;

(2)食源性病毒检测体系的开发与应用。

 

ACADEMIC SALON (XXI)

SPEAKER: Chenang Lyu

  Assistant Research Fellow   

Department of Food Science and Technology

TIME :12:40-14:00  Jun 30, 2021

VENUE:Room 104, Building B, SAB

ORGANIZER:Office of Discipline and Science & Technology, SAB;

Young Teachers Association, SAB

TITLE:Trans-species RNAi and Plant Immunity

ABSTRACT:

Filamentous eukaryotic pathogens, including fungi and oomycetes, are major threats of economically important crops. Most filamentous plant pathogens are biotrophic or hemibiotrophic, engaged in a continuous battle with plant hosts by exchanging active materials to manipulate each other. Oomycetes, such as Phytophthora, are known for secreting a large number of effectors to modulate host immune responses, and accumulating evidence suggests that plant sRNAs can move across species and function as antimicrobial agents against non-viral pathogens. We discovered that plant secondary siRNAs were induced by Phytophthora infection and move into interacting Phytophthora cells. This movement of siRNAs results in decreased expression of Phytophthora transcripts through trans-species RNA interference, thus enhancing plant defense. Therefore, exploiting sRNA transfer mechanisms and engineering siRNA-producing loci could be a useful strategy to engineer crops with improved disease resistance.

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